Showing Publication Results for :

RBPDB
Full Name of the Resource : RNA-binding proteins and their specificities
Resource Category : Databases -> Protein Sequence Databases -> Protein Domain Databases (Protein Classification)

  1. Title of the Paper : RBPDB: a database of RNA-binding specificities (View at PubMed)
    Contributors : Cook, K. B.; Kazan, H.; Zuberi, K.; Morris, Q.; Hughes, T. R.
    Address : Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 3E1, Canada.
    Publication Name : Nucleic Acids Res
    Volume : 39
    Issue : Database issue
    Pages : D301-8
    Publication Year : 2011
    ISSN : 1362-4962 (Electronic) 0305-1048 (Linking)
    Language : English
    Abstract : The RNA-Binding Protein DataBase (RBPDB) is a collection of experimental observations of RNA-binding sites, both in vitro and in vivo, manually curated from primary literature. To build RBPDB, we performed a literature search for experimental binding data for all RNA-binding proteins (RBPs) with known RNA-binding domains in four metazoan species (human, mouse, fly and worm). In total, RPBDB contains binding data on 272 RBPs, including 71 that have motifs in position weight matrix format, and 36 sets of sequences of in vivo-bound transcripts from immunoprecipitation experiments. The database is accessible by a web interface which allows browsing by domain or by organism, searching and export of records, and bulk data downloads. Users can also use RBPDB to scan sequences for RBP-binding sites. RBPDB is freely available, without registration at http://rbpdb.ccbr.utoronto.ca/.