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  1. VFDB (View Publication)
    Full Name of the Resource : Virulence Factors of pathogenic bacteria
    Resource Category : Databases -> Genomic Databases (Non-Human) -> Other Bacteria

    Brief Description : VFDB (http://www.mgc.ac.cn/VFs/) is aimed to provide an in-depth coverage of the major virulence factors (VFs) from various best-characterized bacterial pathogens, with emphasis on functional and structural biology, and essential immunology. This thorough and comprehensive VFDB will be maintained up to date, which would be helpful for researchers to elucidate pathogenic mechanisms in infectious diseases that require further immediate investigations for the development of novel approaches of the disease treatment and prevention. The first release of VFDB contains cumulative information of VFs for 16 important bacteria pathogens, virulence-associated genes, protein structural features, functions, mechanisms and important literatures. Pathogenicity islands, which are clusters of genes encoding virulence traits, are also included. Many graphic illustrations are made according to the original research papers or reviews for an easy grasp of the functions and structures of some VFs. The database is user-friendly; fully searchable by query text or by function categories of VFs, as well as by BLAST comparison against all the VF-related genes.
    Subject Area : Pathogenic Bacteria


    Institute/s :
    1State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing 100176, China 2The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK 3National Center of Human Genome Research, Beijing 100176, China
    Country : China
    Associated Country : China; United Kingdom


    Authors/Contributors : Chen L.H.;; Yang J.; Yu J.; Yao Z.J.; Sun L.L.; Shen Y.; Jin Q.
    Contact Email : VFDB@chgb.org.cn
    Year : 2008

    Keywords : Bacteria / genetics / *pathogenicity; Base Sequence; Computer Graphics; *Databases, Genetic; *Genome, Bacterial; Genomics; Internet; Sequence Alignment; Virulence Factors / *genetics