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  1. UniProt (View Publication)
    Full Name of the Resource : Universal Protein knowledgebase, combined information from Swiss-Prot, TrEMBL, and PIR
    Resource Category : Databases -> Protein Sequence Databases -> General Protein Sequence Databases

    Brief Description : The Swiss-Prot, TrEMBL, and PIR protein database activities have united to form the Universal Protein Resource (UniProt), which provides a central resource on protein sequences and functional annotation with three database components, each addressing a key need in protein bioinformatics. The UniProt Knowledgebase (UniProtKB), comprising the manually annotated UniProtKB/Swiss-Prot section and the automatically annotated UniProtKB/TrEMBL section, is the preeminent storehouse of protein annotation. The extensive cross-references, functional and feature annotations, and literature-based evidence attribution enable scientists to analyze proteins and query across databases. The UniProt Reference Clusters (UniRef) speed similarity searches via sequence space compression by merging sequences that are 100% (UniRef100), 90% (UniRef90), or 50% (UniRef50) identical. Finally, the UniProt Archive (UniParc) stores all publicly available protein sequences, containing the history of sequence data with links to the source databases. The UniProt databases continue to grow in size and in availability of information. New download availability includes all major releases of UniProtKB, sequence collections by taxonomic division, and complete proteomes. A bibliography mapping service has been added, and an ID mapping service will be available soon.
    Subject Area : Universal Protein Resource


    Institute/s :
    EMBL Outstation - The European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, UK
    Address of Institute/s :
    EMBL Outstation - The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    Country : United Kingdom

    Associated Institutes :

    • EMBL Outstation - The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Swiss Institute of Bioinformatics and Department of Structural Biology and Bioinformatics, Centre Medical Universitaire, 1 rue Michel Servet, 1211 Geneva 4, Switzerland
    • Department of Biochemistry and Molecular Biology, Georgetown University Medical Center, Suite 1200, 3300 Whitehaven Street NW, Washington, DC 20007, USA
    • Protein Information Resource, Georgetown University Medical Center, Suite 1200, 3300 Whitehaven Street NW, Washington, DC 20007, USA

    Associated Country : USA; Switzerland


    Authors/Contributors : Apweiler, R.
    Contact Email : apweiler@ebi.ac.uk
    Year : 2011
    Language : English

    Keywords : Databases, Protein / trends; Proteins / chemistry / genetics; Proteomics; Sequence Analysis, Protein; Systems Integration