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  1. TIGR Gene Indices (View Publication)
    Full Name of the Resource : Organism-specific databases of EST and gene sequences
    Resource Category : Databases -> Genomic Databases (Non-Human) -> General Genomics Databases

    Brief Description : Expressed Sequence Tags (ESTs) have provided a first glimpse of the collection of transcribed sequences in a variety of organisms. However, a careful analysis of this sequence data can provide significant additional functional, structural, and evolutionary information. Our analysis of the public EST sequences, available through the TIGR Gene Indices (TGI; http://www.tigr.org/tdb/tdb.html), is an attempt to identify the genes represented by that data and to provide additional information regarding those genes. Gene Indices are constructed for selected organisms by first clustering, then assembling EST and annotated gene sequences from GenBank. This process produces a set of unique, high-fidelity virtual transcripts, or Tentative Consensus (TC) sequences. The TC sequences can be used to provide putative genes with functional annotation, to link the transcripts to mapping and genomic sequence data, and to provide links between orthologous and paralogous genes.
    Subject Area : Expressed Sequence Tags


    Institute/s :
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Country : United States

    Associated Institutes :

    • The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA

    Associated Country : USA


    Authors/Contributors : Quackenbush, J.
    Contact Email : johnq@tigr.org
    Year : 2005
    Language : English

    Keywords : Animals; Base Sequence; Consensus Sequence; *Databases, Genetic / trends; Eukaryotic Cells / metabolism; Expressed Sequence Tags / *chemistry; Genome; *Genomics; Humans; Internet; Sequence Analysis, DNA; Software