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  1. T1Dbase
    Full Name of the Resource : A resource for type 1 diabetes research
    Resource Category : Databases -> Human Genes and Diseases -> Gene-System or Disease-Specific Databases

    Brief Description : T1DBase (http://t1dbase.org/) is a public website and database that supports the type 1 diabetes (T1D) research community. The site is currently focused on the molecular genetics and molecular biology of T1D susceptibility and pathogenesis. It includes the following datasets: annotated genome sequence for human, rat and mouse; information on genetically identified T1D susceptibility regions in human, rat and mouse, and genetic association studies pertaining to T1D; descriptions of NOD mouse congenic strains; the Beta Cell Gene Expression Bank which reports expression levels of genes in beta cells under various conditions, and annotations of gene function in beta cells; data on gene expression in a variety of tissues and organs; and pathways from KEGG and BioCarta. Tools on the site include the GBrowse genome browser, site-wide context dependent search, Connect-the-Dots for connecting gene and other identifiers from multiple data sources, Cytoscape for visualizing and analyzing biological networks, and the GESTALT workbench for genome annotation. All data is open access and all software is open source.

    Institute/s :
    University of Cambridge, Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge, United Kingdom
    Institute for Systems Biology, Seattle, WA, USA
    Free University of Brussels (ULB), Laboratory for Experimental Medicine, Brussels, Belgium
    Wake Forest University School of Medicine, Center for Human Genomics, Winston-Salem, NC, USA

    Country : United Kingdom; Belgium; USA

    Associated Institutes :

    • Institute for Systems Biology Seattle, WA, USA
    • Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, University of Cambridge Cambridge, UK
    • Laboratory of Experimental Medicine, Free University of Brussels (ULB) Brussels, Belgium
    • Center for Human Genomics, Wake Forest University School of Medicine Winston-Salem, NC, USA

    Associated Country : USA; United Kingdom; Belgium


    Authors/Contributors : L.J. Smink
    Contact Email : Luc.Smink@cimr.cam.ac.uk
    Year : 2007
    Language : English