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  1. Polymorphix (View Publication)
    Full Name of the Resource : Database of sequence polymorphisms
    Resource Category : Databases -> Human Genes and Diseases -> General Polymorphism Databases

    Brief Description : Polymorphix is a database of intraspecific sequence polymorphism, structured under the ACNUC (http://pbil.univ-lyon1.fr/databases/acnuc/acnuc.html) sequence database management system. It allows one to select sets of within-(eukaryotic)species sequences families, and to visualize multiple alignments and phylogenetic trees. Polymorphix is useful for meta-analyses of population genomics, and as a bibliographic tool in population genetics. Families in Polymorphix are groups of sequences sharing at least 80% similarity. Multiple alignments were made with Mabios. Outgroup have been added when available (78% similarity required), and aligned to the within-species profile with Clustalv-1.81. Sequence alignments and Neighbour-Joining phylogenetic trees can be viewed. You can use them, together with sequence annotations and bibliographic links, to decide wether the selected families are relevant for your study.

    Institute/s :
    Laboratoire "Génome Populations Interactions Adaptation"
    Address of Institute/s :
    Unité Mixte de Recherche no. 5171 (UMR UM2 - IFREMER - CNRS), Université de Montpellier 2, 34095 Montpellier Cedex 5,
    Country : France

    Associated Institutes :

    • Laboratoire de Biométrie et Biologie Evolutive, Unité Mixte de Recherche n°5558 (UMR UCBL1 - CNRS), Université Claude Bernard-Lyon 1, 69622 Villeurbanne Cedex, France

    Associated Country : France


    Authors/Contributors : Bazin E.; Duret L.; Penel S.; Galtier N.

    Keywords : Animals; *Databases, Nucleic Acid; Genomics; Humans; Phylogeny; *Polymorphism, Genetic; Sequence Alignment; Sequence Homology, Nucleic Acid; User-Computer Interface