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  1. PATRIC (View Publication)
    Full Name of the Resource : PathoSystems Resource Integration Center
    Resource Category : Databases -> Genomic Databases (Non-Human) -> Other Bacteria

    Brief Description : The PathoSystems Resource Integration Center (PATRIC) is one of eight Bioinformatics Resource Centers (BRCs) funded by the National Instituteof Allergy and Infection Diseases (NIAID) to create a data and analysis resource for selected NIAID priority pathogens, specifically proteobacteria of the genera Brucella, Rickettsia and Coxiella, andcorona-, calici- and lyssaviruses and viruses associated with hepatitisA and E. The goal of the project is to provide a comprehensivebioinformatics resource for these pathogens, including consistently annotated genome, proteome and metabolic pathway data to facilitate research into counter-measures, including drugs, vaccines anddiagnostics. The project�s curation strategy has three prongs: "breadthfirst" beginning with whole-genome and proteome curation using standardized protocols, a "targeted" approach addressing the specific needs of researchers and an integrative strategy to leverage high-throughput experimental data (e.g. microarrays, proteomics) and literature. The PATRIC infrastructure consists of a relational database, analytical pipelines and a web site which supports browsing, querying, data visualization and the ability to download raw and curated data in standard formats. At present, the site warehouses complete sequences for 17 bacterial and 332 viral genomes. The PATRIC website (https://patric.vbi.vt.edu) will continually grow with the addition of data, analysis and functionality over the course of the project.
    Subject Area : Pathogenesis


    Institute/s :
    Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University Blacksburg, VA 24061, USA
    Address of Institute/s :
    Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University Blacksburg, VA 24061, USA
    Country : United States

    Associated Institutes :

    • Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University Blacksburg, VA 24061, USA
    • Department of Microbiology and Immunology, Loyola University Medical Center Maywood, IL 60153, USA
    • Center for Human?Computer Interaction, Virginia Polytechnic Institute and State University Blacksburg, VA 24061, USA
    • Department of Microbiology and Immunology, University of Maryland School of Medicine Baltimore, MD 21201, USA
    • VA-MD Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University Blacksburg, VA 24061, USA
    • Centers for Disease Control and Prevention, Atlanta GA 30333, USA



    Authors/Contributors : E. E. Snyder; N. Kampanya; J. Lu; E. K. Nordberg; H. R. Karur; M. Shukla; J. Soneja; Y. Tian; T. Xue; H. Yoo; F. Zhang; C. Dharmanolla; N. V. Dongre; J. J. Gillespie; J. Hamelius; M. Hance; K. I. Huntington; D. Jukneliene; J. Koziski; L. Mackasmiel; S. P. Mane; V. Nguyen; A. Purkayastha; J. Shallom; G. Yu; Y. Guo; J. Gabbard; D. Hix; A. F. Azad; S. C. Baker; S. M. Boyle; Y. Khudyakov; X. J. Meng; C. Rupprecht; J. Vinje; O. R. Crasta; M. J. Czar; A. Dickerman; J. D. Eckart; R. Kenyon; R. Will; J. C. Setubal; B. W. S. Sobral
    Contact Email : esnyder@vbi.vt.edu
    Year : 2007

    Keywords : *Bioterrorism; *Databases, Genetic; Genomics; Internet; Proteobacteria / *genetics / metabolism / pathogenicity; Proteomics; RNA Viruses / *genetics / metabolism / pathogenicity; Systems Integration; User-Computer Interface