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  1. NPInter (View Publication)
    Full Name of the Resource : Noncoding RNA-protein interactions
    Resource Category : Databases -> RNA -> RNA Sequence, Structure and Functions

    Brief Description : The Noncoding RNAs and Protein related biomacromolecules Interaction database (NPInter; http://bioinfo.ibp.ac.cn/NPInter or http://www.bioinfo.org.cn/NPInter) is a database that documents experimentally determined functional interactions between noncoding RNAs (ncRNAs) and protein related biomacromolecules (proteins, mRNAs or genomic DNAs). NPInter intends to provide the scientific community with a comprehensive and integrated tool for efficient browsing and extraction of information on interactions between ncRNAs and protein related biomacromolecules (PRMs). Beyond cataloguing details of these interactions, the NPInter will be useful for understanding ncRNA function, as it adds a very important functional element ? noncoding RNAs - to the biomolecule interaction network and sets up a bridge between the coding and the noncoding kingdoms. By functional interactions we mean both physical interactions between an ncRNA and a protein, and other forms of interaction where the combination of an ncRNA and an mRNA or a genomic DNA sequence elicits a cellular reaction. Although biological knowledge on this sort of interactions is contained in the scientific literature, retrieving it will be much easier with the NPInter database. The database now contains 700 published functional interactions from six model organisms - Escherichia coli, Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila melanogaster, Mus musculus and Homo sapiens. The amount of data is not large, but the NPInter covers almost all experimentally verified functional interactions between ncRNA and PRM published before the end of the year 2004.
    Subject Area : Non-Coding RNA


    Institute/s :
    Bioinformatics Laboratory, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
    Address of Institute/s :
    Bioinformatics Laboratory, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
    Country : China

    Associated Institutes :

    • Bioinformatics Laboratory, Institute of Biophysics, Chinese Academy of Sciences Beijing 100101, China
    • Bioinformatics Research Group, Key Laboratory of Intelligent Information Processing, Institute of Computing Technology Beijing 100080, China
    • Graduate School of the Chinese Academy of Sciences Beijing, China

    Associated Country : China


    Authors/Contributors : Runsheng Chen
    Contact Email : crs@sun5.ibp.ac.cn
    Year : 2005
    Language : English

    Keywords : Animals; DNA / metabolism; Databases, Genetic; Humans; Internet; Mice; RNA, Messenger / metabolism; RNA, Untranslated / classification / metabolism / physiology; RNA-Binding Proteins / metabolism; User-Computer Interface