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  1. MvirDB (View Publication)
    Full Name of the Resource : Protein toxins, virulence factors, and antibiotic resistance genes
    Resource Category : Databases -> Genomic Databases (Non-Human) -> Other Bacteria

    Brief Description : MvirDB (http://mvirdb.llnl.gov/) is a microbial data warehouse of protein toxins, virulence factors, and antibiotic resistance genes for bio-defense applications. MvirDB integrates all publicly available, organized sequence data for protein toxins, virulence factors, and antibiotic resistance genes into a single database, which is easy to access, and which provides value-added annotation information of particular use in bio-defense and medical applications. MvirDB integrates DNA and protein sequence information from several data sources: Tox-Prot, SCORPION, the PRINTS database of virulence factors, VFDB, TVFac, Islander, ARGO, and a subset of VIDA. Entries in MvirDB are hyperlinked back to their original sources. A blast tool allows the user to blast against all DNA or protein sequences in MvirDB, and a browser tool allows the user to search the database to retrieve virulence factor descriptions, sequences, and classifications, and to download sequences of interest. MvirDB has an automated weekly update mechanism. Each protein sequence in MvirDB is annotated using our fully automated protein annotation system (MannDB) and is linked to that system�s browser tool for convenient display of annotation results. We expect to update MvirDB soon to include lists of hand-compiled known virulence factors from the literature and entries from the Snake neurotoxin database, MOLLUSK, and Conotoxins.
    Subject Area : Antibiotic Resistant Genes


    Institute/s :
    Pathogen Bioinformatics, Mailstop L-174 Energy, Environment, and Biology Division, Computations Directorate, Lawrence Livermore National Laboratory, 70000 East Avenue, Livermore, CA 94550, USA 1Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University Blacksburg, VA, USA
    Country : United States


    Authors/Contributors : Zhou C.E.Z.; Smith J.; Lam M.W.; Zemla A.T.; Dyer M.;Slezak T.
    Contact Email : ppi_group@kpath.llnl.gov
    Year : 2007

    Keywords : Bacterial Proteins / chemistry / genetics; Bacterial Toxins / chemistry / genetics; *Bioterrorism; *Databases, Genetic; Drug Resistance, Bacterial / *genetics; Internet; Sequence Analysis, DNA; Sequence Analysis, Protein; Toxins, Biological / *chemistry / *genetics; User-Computer Interface; Viral Proteins / chemistry / genetics; Virulence Factors / *chemistry / *genetics