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  1. Mouse Tumor Biology (View Publication)
    Full Name of the Resource : Tumor types, genes, classification, incidence, pathology
    Resource Category : Databases -> Human and Other Vertebrate Genomes -> Model Organisms, Comparative Genomics

    Brief Description : The Mouse Tumor Biology Database (MTB) is a Web-based resource that provides access to information on tumor frequency, genetics, and pathology in genetically defined mice (i.e., transgenics, targeted mutations, and inbred strains). MTB is designed to serve cancer genetics researchers who use the laboratory mouse as a model system for understanding the genetic and molecular basis of human disease processes. The database can be used to answer such queries as 'What tumors are typically observed in the FVB/N strain?', 'What strains of mice have been reported to develop mammary cancers that subsequently metastasize to the lung?', or 'What tumors in mice are associated with mutations in the Trp53 gene?'. The data represented in MTB are obtained from curation of the primary scientific literature and from direct submissions by members of the scientific community. Existing standards for anatomy, tumor names, gene names, and strain names are enforced to facilitate linking information in MTB to other relevant databases and to ensure completeness and accuracy of the results returned in response to user queries. MTB is accessible from the Mouse Genome Informatics (MGI) Web site (http://www.informatics.jax.org). User support is available via email at mgi-help@informatics.jax.org.

    Institute/s :
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Country : United States

    Associated Institutes :

    • The Jackson Laboratory 600 Main Street, Bar Harbor, Maine, USA

    Associated Country : USA


    Authors/Contributors : Bult C.J.,
    Contact Email : cjb@informatics.jax.org
    Year : 2007
    Language : English

    Keywords : Animals; Hematopoietic Stem Cell Transplantation / methods; Lung / *blood supply; Lung Transplantation / *methods; Mice; *Models, Animal