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  1. InBase (View Publication)
    Full Name of the Resource : Inteins (protein splicing elements) database: properties, sequences, bibliography
    Resource Category : Databases -> Protein Sequence Databases -> Databases of Individual Protein Families

    Brief Description : Inteins are self-catalytic protein splicing elements that interrupt host proteins, called exteins. Extein ligation to form a native peptide bond between the extein segments AND the presence of conserved intein motifs differentiate intein-mediated protein splicing from other post-translational processing events. InBase, the intein Database and Registry, is a curated compilation of published and unpublished information about protein splicing. It provides background material in a separate section called Intein Basics that is suitable for classroom use both on-line and as files to download. However, InBase\'s main focus is to provide detailed information about inteins in a layered format with general discussions and tables pointing to more specific data. Individual intein records contain detailed information about each intein, including comments on unusual properties, submitter contact information and a reference list for each intein. The criteria for intein identification are described, which help differentiate inteins from other types of homing endonuclease genes. An intein-specific BLAST server assists in identifying new inteins. Genome sequencing groups are encouraged to submit intein data and can confidentially request help in finding inteins. The bibliography includes annotations for reviews, application papers, related papers and recent papers. PubMed hot links allow the reader to retrieve abstracts from the National Library of Medicine. Intein data can be submitted confidentially or for immediate release using the on-line Submission Form or by email.
    Subject Area : Inteins, Protein Splicing Elements)


    Institute/s :
    New England Biolabs, 32 Tozer Rd., Beverly, MA 01915, USA
    Address of Institute/s :
    New England Biolabs, 32 Tozer Rd., Beverly, MA 01915, USA
    Country : United States

    Associated Institutes :

    • New England Biolabs Inc., 32 Tozer Road, Beverly, MA 01915, USA

    Associated Country : USA


    Authors/Contributors : Perler, F.B.
    Contact Email : InBase@neb.com
    Year : 2002
    Language : English

    Keywords : Alleles; Amino Acid Motifs; Amino Acid Sequence; Animals; Conserved Sequence; Databases, Protein; Information Storage and Retrieval; Internet; Protein Splicing