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  1. Homophila (View Publication)
    Full Name of the Resource : Drosophila homologs of human disease genes
    Resource Category : Databases -> Human and Other Vertebrate Genomes -> Model Organisms, Comparative Genomics

    Brief Description : Although many human genes have been associated with disease phenotypes, knowing the mutations in one or several disease genes often does not explain the etiology of a specific disease. Drosophila melanogaster provides a powerful system in which to use genetic and molecular approaches to investigate human genetic disease. Homophila is an intergenomic resource linking the human and fly genomes in order to provide a tool for planning functional genomic investigations in Drosophila that address questions about genetic disease in humans. Homophila is a relational database that allows searching based on human disease descriptions, fly phenotypes, human or fly gene names and sequence similarity. Homophila provides a comprehensive linkage between the disease genes compiled in Online Mendelian Inheritance in Man and the complete Drosophila genomic sequence. Homophila is available at http://homophila.sdsc.edu.

    Institute/s :
    San Diego Supercomputer Center, University of California, San Diego, USA
    Address of Institute/s :
    San Diego Supercomputer Center, University of California, San Diego 9500 Gilman Dr. La Jolla CA 92093-0537, USA
    Country : United States

    Associated Institutes :

    • San Diego Supercomputer Center, University of California, San Diego 9500 Gilman Dr. La Jolla CA 92093-0537, USA
    • Department of Biology, University of California, San Diego, 9500 Gilman Dr., La Jolla CA 92093-0349, USA

    Associated Country : USA


    Authors/Contributors : Gribskov, M.
    Contact Email : gribskov@sdsc.edu
    Year : 2002
    Language : English

    Keywords : Animals; DNA Transposable Elements; *Databases, Genetic; Drosophila melanogaster / *genetics; Forecasting; Genes, Insect; Genetic Diseases, Inborn / *genetics; Genome; Humans; Information Storage and Retrieval; Internet; Sequence Homology