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  1. GPCR NaVa database
    Resource Category : Databases -> Protein sequence databases -> Databases of individual protein families

    Brief Description : The GPCR NaVa database describes sequence variants within the family of human G Protein-Coupled Receptors (GPCRs). GPCRs regulate many physiological functions and are the targets for most of today\'s medicines. The acronym NaVa stands for Natural Variant, which means any (non-artificial) variant that occurs in humans. The GPCR NaVa database includes: 1) rare mutations (frequency below 1%); 2) polymorphisms (frequency above 1%), including Single Nucleotide Polymorphisms (SNPs); 3) variants without estimates of allele frequency. The GPCR NaVa database aids GPCR research by categorising and integrating information on variants from databases and scientific papers. Moreover, the GPCR NaVa database is linked with the reputable GPCRDB.

    Institute/s :
    Division of Medicinal Chemistry, Leiden-Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands
    Address of Institute/s :
    Division of Medicinal Chemistry, Leiden-Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands
    Country : Netherlands

    Associated Institutes :

    • Division of Medicinal Chemistry, Leiden-Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands
    • Algorithms Cluster, Leiden Institute of Advanced Computer Science, Leiden University, Leiden, The Netherlands

    Associated Country : Netherlands


    Authors/Contributors : Jeroen Kazius; Kerstin Wurdinger; Maarten van Iterson; Joost Kok; Thomas Back; Ad P. Ijzerman
    Contact Email : j.kazius@lacdr.leidenuniv.nl
    Year : 2001
    Language : English