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  1. European Nucleotide Archive
    Resource Category : Databases -> Nucleotide Sequence Databases -> International Nucleotide Sequence Database Collaboration

    Brief Description : The European Nucleotide Archive provides a comprehensive repository for public nucleotide sequence data, attracting external users from a multitude of research disciplines and serving as underlying data infrastructure for services such as Ensembl, UniProt and ArrayExpress. The foundation for the ENA was the EMBL Data Library, which was established in EMBL Heidelberg in the early 1980s. While this component continues to be operated to this day, the mandate of the ENA has expanded enormously as sequencing technology has advanced and the breadth of applications to which sequencing can now be applied has grown. In recent years, for example, we have launched the Sequence Read Archive (for raw data from next generation sequencing platforms) and have taken responsibility for the operation of the existing European Trace Archive (for raw capillary sequence data), which was previously operated by the Wellcome Trust Sanger Institute. Broadly, ENA captures and presents the whole scale of sequencing information from raw data, through assembly and mapping information that relates very fragmented raw sequence reads into contigs and higher order structures, through to high-level interpretations of the function of parts of nucleic acid molecules, in the form of functional annotation. The ENA achieves comprehensive coverage through partnership with the other global bioinformatics service providers, namely NCBI in the US and DDBJ in Japan. The longest running ENA collaboration, the International Nucleotide Sequence Database Collaboration (INSDC, http://www.insdc.org/), has been underway for over a quarter of a century and now serves as a model for data sharing in the life sciences.

    Institute/s :
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    Address of Institute/s :
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    Country : United Kingdom

    Associated Institutes :

    • European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK

    Associated Country : United Kingdom


    Authors/Contributors : Rasko Leinonen
    Contact Email : rasko@ebi.ac.uk
    Year : 2010