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  1. EPConDB (View Publication)
    Full Name of the Resource : Gene expression in pancreatic development, beta cell function and diabetes
    Resource Category : Databases -> Microarray Data and Gene Expression Databases -> Microarray Data and other Gene Expression Databases

    Brief Description : EPConDB is a public web site that supports research in diabetes, pancreatic development and beta cell function by providing information about genes expressed in cells of the pancreas. EPConDB displays expression profiles for individual genes and information about transcripts, promoter elements and transcription factor binding sites. Gene expression results are obtained from studies examining tissue expression, pancreatic development and growth, differentiation of insulin-producing cells, islet or beta-cell injury, and genetic models of impaired beta cell function. The expression datasets are derived using different microarray platforms, including the BCBC PancChips and Affymetrix gene expression arrays. Other datasets include semi-quantitative RT-PCR and MPSS expression studies. For selected microarray studies, lists of differentially expressed genes, derived from PaGE analysis, are displayed on the site. EPConDB provides database queries and tools to examine the relationship between a gene, its transcriptional regulation, protein function and expression in pancreatic tissues.

    Institute/s :
    Department of Genetics, School of Medicine, and Center for Bioinformatics, University of Pennsylvania, Philadelphia, PA 19104
    Country : United States

    Associated Institutes :

    • Department of Genetics, School of Medicine, Center for Bioinformatics, University of Pennsylvania Philadelphia, PA 19104, USA

    Associated Country : USA


    Authors/Contributors : Manduchi, E.,
    Contact Email : manduchi@pcbi.upenn.edu
    Year : 2007
    Language : English

    Keywords : Animals; Binding Sites; *Databases, Genetic; Diabetes Mellitus / *genetics / metabolism; Gene Expression Profiling; Humans; Insulin-Secreting Cells / *metabolism; Internet; Mice; Oligonucleotide Array Sequence Analysis; Pancreas / growth & development / *metabolism; Promoter Regions, Genetic; Software; Transcription Factors / metabolism; *Transcription, Genetic; User-Computer Interface