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  1. DSD (View Publication)
    Full Name of the Resource : Database of dehydrogenase stereospecificities
    Resource Category : Databases -> Protein Sequence Databases -> Databases of Individual Protein Families

    Brief Description : Dehydrogenase enzymes belong to the oxidoreductase class and utilise the coenzymes NAD and NADP. Stereo-selectivity is focused on the C4 hydrogen atoms of the nicotinamide ring of NAD(P). Depending upon which hydrogen is transferred at the C4 location, the enzyme is designated as A or B stereospecific. The Dehydrogenase Stereospecificity Database v1.0 (DSD) provides a compilation of enzyme stereochemical data, as sourced from the primary literature, in the form of a web-accessible database. There are two search engines, a menu driven search and a BLAST search. The entries are also linked to several external databases, including the NCBI and the Protein Data Bank, providing wide background information. The database is freely available online at: http: / / www.jenner.ac.uk / DSD / DSD is a unique compilation available on-line for the first time which provides a key resource for the comparative analysis of reductase hydrogen transfer stereospecificity. As databases increasingly form the backbone of science, largely complete databases such as DSD, are a vital addition.
    Subject Area : Dehydrogenase Enzymes


    Institute/s :
    The Jenner Institute, University of Oxford, High Street, Compton, Berkshire, UK, RG20 7NN
    Address of Institute/s :
    The Jenner Institute, University of Oxford, High Street, Compton, Berkshire, UK, RG20 7NN
    Country : United Kingdom

    Associated Institutes :

    • The Jenner Institute, University of Oxford, High Street, Compton, Berkshire, UK, RG20 7NN

    Associated Country : United Kingdom


    Authors/Contributors : Flower, D.R.
    Contact Email : Darren.Flower@jenner.ac.uk
    Year : 2005
    Language : English

    Keywords : Computational Biology / methods; Databases, Factual; Databases, Nucleic Acid; Databases, Protein; Enzymes / chemistry; Hydrogen / chemistry; Information Services; Information Storage and Retrieval; Internet; Oxidoreductases / chemistry / genetics; Protein Folding; Proteins / chemistry; Stereoisomerism; Substrate Specificity