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  1. DBTGR (View Publication)
    Full Name of the Resource : Database of tunicate Ciona gene regulation
    Resource Category : Databases -> Human and Other Vertebrate Genomes -> Model Organisms, Comparative Genomics

    Brief Description : Tunicates are lower chordates that include among others the two ascidians Ciona intestinalis and Ciona savignyi. This subphylum is particularly interesting because it shares many developmental and physiological characteristics, as well as basic gene repertoires, with vertebrates. The recent sequencing of two different Ciona genomes has lead to the identification of numerous genes. In order to better understand the regulation of these genes, DBTGR, a DataBase of Tunicate Gene Regulation, was created. It contains information on regulation of tunicate genes collected from literature, such as the minimal promoter length, the transcription factors involved and their binding sites or the localization of the gene expression, as well as binding sites for characterized transcription factors predicted based on published in vitro recognition sites. To allow identification of conserved cis elements, comparison of the promoters of homologous genes in both species is also provided.

    Institute/s :
    Human Genome Center, IMS, University of Tokyo
    Department of Life Science, Graduate School of Life Science, University of Hyogo
    Structure and Function of Biomolecules, SORST, JST

    Country : Japan

    Associated Institutes :

    • Human Genome Center, The Institute of Medical Science, University of Tokyo 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan
    • Department of Life Science, Graduate School of Life Science, University of Hyogo 3-2-1 Kouto, Kamigori, Ako-gun, Hyogo 678-1297, Japan
    • Structure and Function of Biomolecules, SORST, JST 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan

    Associated Country : Japan


    Authors/Contributors : Nakai K.
    Contact Email : knakai@ims.u-tokyo.ac.jp
    Year : 2006
    Language : English

    Keywords : Animals; Base Sequence; Binding Sites; Computer Graphics; *Databases, Nucleic Acid; Gene Expression Regulation; Internet; Larva / genetics / metabolism; *Promoter Regions, Genetic; Sequence Alignment; Transcription Factors / *metabolism; Urochordata / *genetics / growth & development / metabolism; User-Computer Interface