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  1. DBTBS (View Publication)
    Full Name of the Resource : Bacillus subtilis promoters and transcription factors
    Resource Category : Databases -> Genomic Databases (Non-Human) -> Bacillus subtilis

    Brief Description : With the entire genome sequence of Bacillus subtilis now determined, one of the next major targets of B. subtilis genomics is to elucidate its complete gene regulatory network. To this end, the results of systematic experiments should be compared with the rich source of individual experimental results accumulated so far. We therefore constructed the DBTBS database, containing a collection of experimentally validated gene regulatory relations and the corresponding transcription factor binding sites upstream of B. subtilis genes. Its current version is constructed by surveying 873 references and contains the information of 116 binding factors and 1253 gene regulatory relations. For each promoter, all of its known cis-elements are listed according to their positions, while these cis-elements are aligned to illustrate the consensus sequence for each transcription factor. All probable transcription factors coded in the genome were classified using Pfam motifs. Multiple alignments of upstream sequences between B. halodurans, B. stearothermophilus, and B. subtilis are also shown.
    Subject Area : Transcriptional Regulation Events in Bacillus subtilis


    Institute/s :
    Human Genome Center, The Institute of Medical Science, University of Tokyo, Tokyo 108?]8639, Japan
    Address of Institute/s :
    Human Genome Center, The Institute of Medical Science, University of Tokyo, Shirokanedai, Minatoku, Tokyo, Japan.
    Country : Japan

    Associated Institutes :

    • Human Genome Center, The Institute of Medical Science, University of Tokyo, Shirokanedai, Minatoku, Tokyo Japan
    • Department of Applied Physics, Graduate School of Engineering, Nagoya University, Chikusaku, Nagoya, Japan
    • Department of Bioinformatics and Genomics, Graduate School of Information Science, Nara Institute of Science and Technology, Takayama, Ikoma, Nara, Japan

    Associated Country : Japan


    Authors/Contributors : Yuko Makita; Mitsuteru Nakao; Naotake Ogasawara; Kenta Nakai
    Contact Email : knakai@ims.u-tokyo.ac.jp
    Year : 2003

    Keywords : Bacillus subtilis / genetics; Base Sequence; Binding Sites; Conserved Sequence; DNA, Bacterial / chemistry; DNA, Intergenic / chemistry; Databases, Genetic; Gene Expression Regulation, Bacterial; Genomics; Gram-Positive Bacteria / genetics; Internet; Operon; Promoter Regions, Genetic; Regulatory Elements, Transcriptional; Sequence Alignment; Transcription Factors / metabolism