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  1. DBD
    Resource Category : Databases -> Nucleotide Sequence Databases -> Transcriptional Regulator Sites and Transcription Factors

    Brief Description : DBD provides transcription factor predictions for more than 150 completely sequenced genomes available for browsing and download. Predictions are based on presence of sequence specific DNA binding domain assignments using hidden Markov models from the SUPERFAMILY and PFAM databases. Evaluation shows that our predictions are 97% accurate and give at least 65% coverage. Focusing on individual genomes show that DBD identifies many novel factors for example, corresponding to a 90% increase in the known mouse transcription factor repertoire. Users can browse factors by genome or domain type, search for particular factors or submit a sequence for prediction.

    Institute/s :
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK
    Address of Institute/s :
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK
    Country : United Kingdom

    Associated Institutes :

    • MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK

    Associated Country : United Kingdom


    Authors/Contributors : Derek Wilson; Varodom Charoensawan; Sarah K. Kummerfeld; Sarah A. Teichmann
    Contact Email : skk@mrc-lmb.cam.ac.uk
    Year : 2007