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  1. CutDB (View Publication)
    Full Name of the Resource : Community annotation resource for proteases, their substrates and cleavage sites
    Resource Category : Databases -> Metabolic and Signaling Pathways -> Protein-Protein Interactions

    Brief Description : CutDB is one of the first systematic efforts to build an easily accessible collection of documented proteolytic events for natural proteins in vivo or in vitro. A CutDB entry is defined by a unique combination of these three attributes: protease, protein substrate, and cleavage site. Currently, CutDB integrates 3,070 proteolytic events for 470 different proteases captured from public archives (such as MEROPS and HPRD) and publications. CutDB supports various types of data searches and displays, including clickable network diagrams. Most importantly, CutDB is a community annotation resource based on a Wikipedia approach, providing a convenient user interface to input new data online. A recent contribution of 568 proteolytic events by several experts in the field of matrix metallopeptidases suggests that this approach will significantly accelerate the development of CutDB content. CutDB is publicly available at

    Institute/s :
    Burnham Institute for Medical Research, La Jolla, California 92037, USA
    Address of Institute/s :
    Burnham Institute for Medical Research, La Jolla, California 92037, USA
    Country : United States

    Associated Institutes :

    • Burnham Institute for Medical Research, 10901 North Torrey Pines Road La Jolla, CA 92037, USA

    Associated Country : USA

    Authors/Contributors : Yoshinobu Igarashi; Alexey Eroshkin; Svetlana Gramatikova; Kosi Gramatikoff; Ying Zhang; Jeffrey W. Smith; Andrei L. Osterman; Adam Godzik
    Contact Email :
    Year : 2007
    Language : English

    Keywords : Animals; *Databases, Protein; Humans; Internet; Peptide Hydrolases / *metabolism; Substrate Specificity; User-Computer Interface