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  1. CoryneRegNet (View Publication)
    Full Name of the Resource : Corynebacterial transcription factors
    Resource Category : Databases -> Genomic Databases (Non-Human) -> Other Bacteria

    Brief Description : CoryneRegNet is an ontology-based data warehouse for the reconstruction and visualization of transcriptional regulatory interactions in prokaryotes. To extend the biological content of CoryneRegNet, we added comprehensive data on transcriptional regulations in the model organism Escherichia coli K-12, originally deposited in the international reference database RegulonDB. The enhanced web interface of CoryneRegNet offers several types of search options. The results of a search are displayed in a table-based style and include a visualization of the genetic organization of the respective gene region. Information on DNA binding sites of transcriptional regulators is depicted by sequence logos. The results can also be displayed by several layouters implemented in the graphical user interface GraphVis, allowing, for instance, the visualization of genome-wide network reconstructions and the homology-based inter-species comparison of reconstructed gene regulatory networks.
    Subject Area : Cynobacteria


    Institute/s :
    Computational Systems Biology, Max Planck Institute for Informatics, Campus E1.4, 66123 Saarbrucken,
    Address of Institute/s :
    Computational Systems Biology, Max Planck Institute for Informatics, Campus E1.4, 66123 Saarbrucken,
    Country : Germany

    Associated Institutes :

    • Computational Systems Biology, Max Planck Institute for Informatics, Campus E1.4, 66123 Saarbrucken, Germany
    • Cluster of Excellence for Multimodal Computing and Interaction, Saarland University, Campus E1.7, 66123 Saarbrucken, Germany
    • Center for Biotechnology, Bielefeld University, D-33594 Bielefeld, Germany
    • Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Belo Horizonte MG, Brazil

    Associated Country : Germany; Brazil


    Authors/Contributors : Josch Pauling; Richard Rottger; Andreas Tauch; Vasco Azevedo; Jan Baumbach
    Contact Email : jbaumbac@mpi-inf.mpg.de
    Year : 2011

    Keywords : Computational Biology / *methods; Corynebacterium / *genetics; *Databases, Genetic; *Gene Expression Regulation, Bacterial; *Gene Regulatory Networks; Internet; Transcription Factors / genetics; Transcription, Genetic; User-Computer Interface