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  1. ChimerDB (View Publication)
    Full Name of the Resource : ChimerDB
    Resource Category : Databases -> Human Genes and Diseases -> Cancer Gene Databases

    Brief Description : ChimerDB is a database of fusion sequences encompassing bioinformatics analysis of mRNA
    Subject Area : mRNA


    Institute/s :
    Division of Molecular Life Sciences, Ewha Womans University, Korea.
    Address of Institute/s :
    Division of Molecular Life Sciences, Ewha Womans University, Seoul 120-750, Korea
    School of Chemistry, Seoul National University, Seoul 151-747, Korea

    Country : Korea

    Associated Institutes :

    • Division of Molecular Life Sciences, Ewha Womans University, Seoul 120-750, Korea
    • School of Chemistry, Seoul National University, Seoul 151-747, Korea

    Associated Country : Korea


    Authors/Contributors : Kim, N.
    Contact Email : sanghyuk@ewha.ac.kr
    Year : 2006
    Language : English

    Keywords : Animals; *Databases, Nucleic Acid; Expressed Sequence Tags/chemistry; *Gene Fusion; Genomics; Humans; Internet; Mice; Mutant Chimeric Proteins/*genetics/metabolism; RNA, Messenger/chemistry; Rats; User-Computer Interface


  2. ChimerDB (View Publication)
    Full Name of the Resource : Chimeric (fusion) sequences in human, rat and mouse
    Resource Category : Databases -> Nucleotide Sequence Databases -> Gene Structure, Introns and Exons, Splice Sites

    Brief Description : ChimerDB is a database of fusion sequences encompassing bioinformatics analysis of mRNA and EST sequences in the GenBank, manual collection of literature data and integration with other well known databases. Fusion transcripts with nonoverlapping alignments at multiple genomic loci were identified and filtered to remove cloning artifacts in cDNA library preparation. Fusion transcripts are classified into two groups - genuine chromosome translocation and fusion between neighboring genes owing to intergenic splicing. Literature data from pubmed abstracts and the fusion data from public resources (OMIM, Sanger CGP, Atlas chromosomes in cancer, and the Mitelman's breakpoint) are integrated to enhance the coverage and reliability. Currently, ChimerDB contains 1,258 fusion cases that involve 1,777 genes, 381 mRNA and 654 EST sequences. It can be accessed at http://genome.ewha.ac.kr/ChimerDB/.
    Subject Area : mRNA and Expressed Seqience Tag sequences


    Institute/s :
    Division of Molecular Life Sciences, Ewha Womans University, Korea
    Address of Institute/s :
    Division of Molecular Life Sciences, Ewha Womans University, Seoul 120-750, Korea
    Country : Korea

    Associated Institutes :

    • Division of Molecular Life Sciences, Ewha Womans University Seoul 120-750, Korea
    • Interdisciplinary Program in Bioinformatics, Seoul National University Seoul 151-747, Korea
    • School of Chemistry, Seoul National University Seoul 151-747, Korea

    Associated Country : Korea


    Authors/Contributors : Sanghyuk Lee
    Contact Email : sanghyuk@ewha.ac.kr
    Year : 2006
    Language : English

    Keywords : Animals; *Databases, Nucleic Acid; Expressed Sequence Tags/chemistry; *Gene Fusion; Genomics; Humans; Internet; Mice; Mutant Chimeric Proteins/*genetics/metabolism; RNA, Messenger/chemistry; Rats; User-Computer Interface