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  1. BioGRID (View Publication)
    Full Name of the Resource : Genetic and physical interactions in yeast, worm and fly
    Resource Category : Databases -> Metabolic and Signaling Pathways -> Protein-Protein Interactions

    Brief Description : Access to unified datasets of protein and genetic interactions is critical for interrogation of gene/protein function and analysis of global network properties. BioGRID is a freely accessible database of physical and genetic interactions available at http://www.thebiogrid.org. BioGRID release version 2.0 includes more than 116,000 interactions from Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila melanogaster and Homo sapiens. An internally hyper-linked web interface allows for rapid search and retrieval of interaction data. Full or user-defined datasets are freely downloadable as tab-delimited text files and PSI-MI XML. Pre-computed graphical layouts of interactions are available in a variety of file formats. User-customized graphs with embedded protein, gene and interaction attributes can be constructed with a visualization system called Osprey that is dynamically linked to the BioGRID.

    Institute/s :
    Ontario Cancer Institute, Princess Margaret Hospital, 610 University Avenue, Toronto, Ontario M5G 2M9, Canada
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto Ontario M5G 1X5, Canada
    Department of Medical Genetics and Microbiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada

    Country : Canada

    Associated Institutes :

    • Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, Canada
    • School of Biological Sciences, University of Edinburgh, Mayfield Road, Edinburgh, EH9 3JR Scotland, UK
    • Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA
    • California Institute of Technology, Division of Biology 156-29, Pasadena, CA 91125, USA
    • Ontario Institute For Cancer Research, Toronto, ON M5G 0A3, Canada

    Associated Country : Canada; United Kingdom; USA


    Authors/Contributors : Tyers M.
    Contact Email : tyers@mshri.on.ca
    Year : 2011
    Language : English